Detalhe da pesquisa
1.
Overexpression of ABCC1 and ABCG2 confers resistance to talazoparib, a poly (ADP-Ribose) polymerase inhibitor.
Drug Resist Updat
; 73: 101028, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38340425
2.
ABCB1-dependent collateral sensitivity of multidrug-resistant colorectal cancer cells to the survivin inhibitor MX106-4C.
Drug Resist Updat
; 73: 101065, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38367548
3.
Design, synthesis, and biological evaluation of phenylurea indole derivatives as ABCG2 inhibitors.
Bioorg Chem
; 135: 106481, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36966672
4.
Multidrug resistance proteins (MRPs): Structure, function and the overcoming of cancer multidrug resistance.
Drug Resist Updat
; 54: 100743, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513557
5.
Dual TTK/CLK2 inhibitor, CC-671, selectively antagonizes ABCG2-mediated multidrug resistance in lung cancer cells.
Cancer Sci
; 111(8): 2872-2882, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32478948
6.
Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells.
Int J Mol Sci
; 21(4)2020 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32092870
7.
PBK/TOPK inhibitor OTS964 resistance is mediated by ABCB1-dependent transport function in cancer: in vitro and in vivo study.
Mol Cancer
; 21(1): 40, 2022 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35135547
8.
Design, Synthesis and Biological Evaluation of Quinazolinamine Derivatives as Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors with Improved Metabolic Stability.
Biomolecules
; 13(2)2023 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36830622
9.
Cytotoxicity and reversal effect of sertraline, fluoxetine, and citalopram on MRP1- and MRP7-mediated MDR.
Front Pharmacol
; 14: 1290255, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38026953
10.
Understanding and targeting resistance mechanisms in cancer.
MedComm (2020)
; 4(3): e265, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37229486
11.
The Resistance of Cancer Cells to Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, is Mediated by the ABCB1 Transporter.
Front Pharmacol
; 13: 861642, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35350768
12.
Anticancer effect of Indanone-based thiazolyl hydrazone derivative on p53 mutant colorectal cancer cell lines: An in vitro and in vivo study.
Front Oncol
; 12: 949868, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35992866
13.
Overexpression of ABCB1 Associated With the Resistance to the KRAS-G12C Specific Inhibitor ARS-1620 in Cancer Cells.
Front Pharmacol
; 13: 843829, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35281897
14.
MET inhibitor tepotinib antagonizes multidrug resistance mediated by ABCG2 transporter: In vitro and in vivo study.
Acta Pharm Sin B
; 12(5): 2609-2618, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35646541
15.
Signaling pathways and therapeutic interventions in gastric cancer.
Signal Transduct Target Ther
; 7(1): 358, 2022 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36209270
16.
Preclinical studies of the triazolo[1,5-a]pyrimidine derivative WS-716 as a highly potent, specific and orally active P-glycoprotein (P-gp) inhibitor.
Acta Pharm Sin B
; 12(8): 3263-3280, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35967279
17.
Discovery of the Triazolo[1,5-a]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance.
J Med Chem
; 64(21): 16187-16204, 2021 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34723530
18.
Insights on the structure-function relationship of human multidrug resistance protein 7 (MRP7/ABCC10) from molecular dynamics simulations and docking studies.
MedComm (2020)
; 2(2): 221-235, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34766143
19.
Overexpression of ABCG2 Confers Resistance to MLN7243, a Ubiquitin-Activating Enzyme (UAE) Inhibitor.
Front Cell Dev Biol
; 9: 697927, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34336849
20.
Overcoming multidrug resistance by knockout of ABCB1 gene using CRISPR/Cas9 system in SW620/Ad300 colorectal cancer cells.
MedComm (2020)
; 2(4): 765-777, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34977876